I kind of decide case-by-case, but with Facebook in particular I'm a bit extra careful just because you see so much app spam in people's feeds. Also, I think this is the same Sara Project app that was built as a Siri alternative, and I'm not really clear about where it's sending the photos you upload.
Might just wait to see if it's in iOS 6, or I might check out FBUploader or iSocialShare, which have been out for a while. Those two are paid tweaks; Facebookthis is free so I thought I'd ask.
So far I've notice that it doesn't work on my iPhone4, but does work on my wifes iPhone4s. Both are JB and running the same ios and JB.....just doesn't like my ip4. I've uninstalled and reinstalled 3x now.