What is worrying you? It's a different interface but with cloud storage it's easy for the majority of users to overcome not having a traditional file system.
Hmm...You just can't do a lot of things on iPad Pro and cloud service is not the best choice:
1. Cloud storage costs additional money if we are talking about icloud
2. 3rd party CS apps, like Mega, have problems with saving and opening files on the device
3. Backgroud tasks are still very limited on iOs
4. Advanced web browsing with plugins, advanced photo-video editing with multi-monitor setup are not possible
5. Developing, even simple enough
6. Sending files to my eBook or Music Player (not iPod)
7. Really productive multitasking with a lot of windows, tabs and displays connected (even for work with text and writing an article it is worse on iOs)
8. You can run windows if you need it sometimes on mac
9. You can find any app you want without app store and a lot of them are free or have trial period if you need it once - this all is possible only on mac
10. I still think mobile gaming is stupid waste of time, but there are some interesting games on mac (or windows, remember?)
So, enough. Mac is just better here. iPad would be an option, if it had desktop-class OS, for now - it is just a toy.