If I tell Siri to remind me to do something, and then ask it to remind me to do something else, both reminders are visible in my to-do list via the native Reminders app. In your post, you mentioned, "notes". Is that the name of the To-Do list app or are you referring to the native Notes app? If the native Notes app, you can tell Siri to create a note for you and then tell her to add to a note. She will ask which note you want to add to, and therefore, the answer to your question is yes.