With your current ecosystem being solidly in the Apple camp, I think that you may enjoy the seamless integration of an iPhone more than an Android phone.
However, I own the original Moto X and think that it's the best Android phone out there. It's not my favorite phone, though. I know that it seems weird but the only thing that I didn't like about the original Moto X was the small screen size. The 2014 Moto X will resolve that and make me a happy camper when I get it.
There are people who integrate their Android devices with an Apple ecosystem, so it can be done. You would probably lose iCloud syncing, though. I'm not familiar with iCloud syncing so someone else can guide you on this further.
If you approach it with an open mind, you can adjust to a Moto X. While it would be somewhat similar because the iPhone and the Moto X are both smartphones, there will be differences that you will have to adjust to. Why are you thinking about giving up the iPhone 6 Plus?