My home screen is incredibly boring. Because I have a few devices, and I do a lot of testing with them, I also have to restore them fairly often and it's gotten to the point where I just leave everything in its default location because it's a) easier than rearranging and b) I don't have to hunt for stuff I haven't rearranged.
So, my second screen has become where I move my non-default, but still more often used apps. Typically the exact order will vary due to the reasons above, but the apps are fairly consistent.
Top row is secondary Apple apps, which I use once-and-a-while but like to refer back to. Next is UDID so I can quickly get an Ad Hoc distro set up if I need to test something. 1Password is typically the first thing that goes onto my Macs and iPhones. Life. Saver. BeeJiveIM is for those rare occasions I keep IM on, on the go. Qik is the Ad Hoc version that actually does stream live (Apple/AT&T need to approve that version now). TWiT.am is for when I want to listen to streaming Leo Laporte. Wikipanion gets hit often for pop culture reference. Jaadu hasn't been set up in a while, but I dream of it working for remote desktop one day. Skype just came to Canada, but only works on full bar WiFi right now. TwitBit 2.0 is what I'm testing for Twitter right now. Tweetie is just so Apple-like I often default back to it for power posting. Shazam is Shazam. It might get banished to a lower screen soon. Navigon keeps me from getting lost, which I am wont to do.
What's on your home screen and why? Show us a screen shot (hold down Home + Sleep button to save to your Photo app) and let us know the deets!
right now, i primarily put my 'most used' apps on 1st page. no particular order on the page itself. i do keep my messaging apps and browser on my dock. i use those all the time so i want easy access to these apps. i am, however, very close to adding Pandora onto my main page. i use it a TON when i'm working away from my computer.
currently, i have 6 pages of apps. and i'm thinking of thinning that out soon. just don't use 1/2 the apps i have on there. i really like Categories and Winterboard (JB apps). gives me a different look from most of my friends and family (of whom many are turning to iPhones).
if it's not on the main page, i generally find it using Spotlite/Spotbrite. i don't flick through pages looking for things. that's also why i like Categories. keeps the app clutter down. and with the addition of Spotbrite (JB app) i can search for apps within my Categories folders too. another nice feature.
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* iPhone 4S 32GB, iOS 5
* iPad 32GB WiFi only, iOS 5
Here's mine. Obviously jailbroken. Nothing too interesting going on, but I think it looks clean. I have my camera application hidden, but my home button double clicks to open it. photo-1.jpg
Here's mine. I like to keep my home screen limited to applications that I use each and every day. The rest of my home screens are organized by category, with the very last page for the stock apps that I never use.
why is the first one so clear compared to the second one? haha
mine is all the default icons but I added Bank of america and AT&T wireless so i can check both accounts easily and the Weather Channel because sometimes that weather is a lot more accurate then the default weather app.
With that coverflow dock you have to have those icons specifically where they are. I dont always have the coverflow on so this is what my home looks like with and without it.
Keep my Google Voice, Skype, Notespark, Textfree among others on my home screen. I tried not to overcrowd with icons and pick a background that will not have contrasting problems with icon text.
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What's on YOUR iPhone Home Screen? 
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