Help! My I-phone 5S won't allow me to slide to open or slide to power off.

I

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I purchased it in 2013. It hasn't gotten wet, although it has been dropped a few times. It will allow calls to come in, and I can call out while using the SYNC in my car. Any ideas?
 

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Hold down both the Power and Home buttons concurrently until the device reboots itself, this usually takes about 10 seconds, as signified by the  Apple logo appearing on screen